Establishment of a Molecular Embryonic Stem Cell Developmental Toxicity Assay
نویسندگان
چکیده
منابع مشابه
Effects of Mouse Strain on Establishment of Embryonic Stem Cell Lines
Purpose: Embryonic stem (ES) cells are derived from the inner cell mass of blastocysts with self-renewal and pluripotency characteristics. These cells have potential for studies of in vitro differentiation, gene function, etc. This study was, therefore, initiated to establish new ES lines and evaluate the effects of strain on ES cell production. Materials and Methods: 3-5 day blastocysts were ...
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Studies of the biology of human embryonic stem cells (hES cells) have developed rapidly over the past nine years since the first reports of their derivation. They clearly offer enormous potential, not only for regenerative medicine, but also for drug discovery and toxicology, human developmental biology and cancer research. Realizing these potentials a better understanding of the fundamental as...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2012
ISSN: 1096-6080,1096-0929
DOI: 10.1093/toxsci/kfs293